Instructions for use of the drug Mezim

Causes and signs of intoxication

Poisoning or intoxication can occur suddenly when eating spoiled food, overdosing on alcohol, or smoking a large number of cigarettes.

Failure to comply with basic hygiene rules, dirty hands, unwashed fruits and vegetables can cause E. coli to enter the body, causing poisoning, accompanied by nausea, vomiting, diarrhea, fever and other symptoms.

If the victim is in a state of mild poisoning, he can be helped without contacting a doctor. You should rinse your stomach, give you the necessary absorbents, enzymes, and painkillers to drink. After removing the main symptoms, the patient should be given warm, sweet tea and put to bed.

In case of more serious poisoning, you must call an ambulance. The patient must be transported to a medical facility, where he must undergo symptomatic drug treatment.

Composition and properties of the drug

The main active ingredient of Mezim is powder from the pork pancreas - pancreatin. The “stronger” the medicine, the higher the concentration of the component. Minimal enzyme activity consists of proteases, lipases and amylases.

The drug also contains auxiliary components:

• anhydrous silica;
• sodium starch glycolate;
• MCC;
• Mg stearate;
• talc;
• hypromellose;
• macrogol 6000;
• simethicone emulsion.

Pancreatitis contains excretory type enzymes and is used by the body to digest essential substances - fats, carbohydrates and proteins. After consuming the drug, the process occurs easier and faster, which leads to the absorption of substances in the small intestine.

Trypsin , which is part of pancreatin, suppresses pancreatic secretion, relieving pain symptoms when gastric functions are impaired. The drug begins to act within 30 minutes after taking Mezim.

First aid to the victim

In case of any intoxication, you must first thoroughly rinse the stomach and empty it of alcohol-containing drinks, spoiled products, mushrooms, etc.

1. To do this, give the victim a drink of one and a half liters of boiled water with potassium permanganate and induce vomiting by pressing on the root of the tongue with your fingers. Continue the procedure until the water becomes clear, without pieces of food.
2. Next, the patient should be given a cleansing enema. It will take a series of enemas to get clear water coming out. You should not cleanse your intestines if you have severe diarrhea.
3. These procedures are possible if the person is in a conscious state. Enemas and gastric cleansing should not be performed on infants and the elderly.
4. Next, you need to give the victim absorbents that will help the body get rid of toxins that have entered the blood and prevent their further absorption. Smecta, Polysorb, Phosphalugel are suitable for this.
5. After an hour to an hour and a half, in order to relieve spasms and pain in the gastrointestinal tract, the patient needs to be given antispasmodics, these are No-shpa, Drotaverine and Spazmalgon. To start and stabilize the digestive process in the gastrointestinal tract, you need to take two Mezim tablets.
6. Compotes, sweet tea, rosehip or chamomile decoctions normalize the water-salt balance in the body. To avoid triggering the gag reflex again, you should drink the liquid slowly and in small sips.

Absorbents should be given separately from other medications so that beneficial microelements and active substances of the medications taken do not leave the body along with toxic substances.

An effective remedy – Mezim for constipation

It is not customary to talk out loud about the difficulties of defecation, but it is known that most residents of developed countries are familiar with this condition. It is characterized by stool retention for more than 48 hours or daily bowel cleansing associated with difficulty in passing too little feces (less than 100 g).

This condition occurs under the influence of various factors. These include stress, a sedentary lifestyle, and a diet consisting mainly of refined foods that have undergone long-term heat treatment.

Last but not least are intestinal neoplasms and chronic diseases of the digestive system. Problems with one of the vital organs, the pancreas, also cause intestinal dysfunction.

One of the symptoms of the disorder is diarrhea. But quite often, constipation appears along with gland disease. Insufficient production of digestive enzymes and bile deficiency prevent food from being digested normally.

Because of this, fragments of what you eat accumulate and stagnate. The diseased organ itself accumulates its own catalysts that act destructively. The longer this goes on, the more serious the problem.

The destroyed glandular tissue is replaced by scars, which gradually leads to atrophy of the organ. A malfunction in the cleansing function is a consequence of improper synthesis of enzymes.

If a small amount of active substances comes from the pancreas, what is eaten is not processed by the body:

• fats with lipase deficiency;
• proteins – proteases;
• carbohydrates - amylases.

Inflammation of the pancreas (pancreatitis), other pathologies are accompanied by difficulty in defecation, as well as:

• accumulation of large amounts of gases;
• pain in the intestines;
• water balance disturbance.

In addition to such disorders, excess at the table worsens the functioning of the pancreas. Especially on holidays, when a wide variety of fatty foods, meats, smoked foods, sweet pastries, and alcohol are offered.

After feasts, there is a feeling of heaviness, bloating, and almost always - stagnation of waste products. Many people try to get rid of unpleasant sensations by taking tablets containing enzymes.

A drug that improves digestion

Medicines that compensate for the deficiency of lipase, amylase, and protease were first used more than 100 years ago. Today they are prescribed by gastroenterologists to patients with serious disorders. But many people buy them without consulting a doctor, so that they can always have them on hand “just in case.”

Mezim is among the most popular drugs. The main active ingredient is pancreatin, which includes protease, amylase, lipase. The product is produced using pork and cow pancreas.

For the treatment of conditions associated with stool disorders, manifested by prolonged constipation, as well as weakened motor activity of the gastrointestinal tract, the drug should be prescribed exclusively by a specialist. The doctor also determines the required dosage and duration of therapy.

The doctor calculates the number of tablets that will have to be taken based on the severity of his patient’s condition. You can draw a conclusion about the effectiveness of treatment if:

• the patient stopped complaining of pain;
• the frequency of productive visits to the toilet has normalized;
• the consistency and density of the stool has changed.

Improvements are also noticeable in laboratory analysis results.

Taking a pill after a hearty lunch or a hearty dinner, you can expect that after a short time (an hour and a half) the feeling of fullness and heaviness in the stomach will go away. There will be no stagnation of intestinal contents.

That is why, when answering the question of whether Mezim helps with constipation, gastroenterologists answer in the affirmative. The product is recommended for use by persons suffering from instability of gastric motor function.

There is practically no risk of heartburn, belching, or other very unpleasant phenomena; this is due to the absence of bile acids in the composition of the drug.

In addition to the weak exocrine activity of the gland, which causes a lack of enzymes, the remedy is also used for other pathologies:

• cystic fibrosis, a genetically determined disease characterized by the accumulation of large amounts of mucus in the lungs and bronchi;
• diseases of the small, large intestine, stomach;
• problems with the liver, gall bladder, dyskinesia of the bile ducts.

How to take Mezim

The medicine is produced in the form of biconvex tablets, coated, dissolving inside the small intestine. To avoid damaging the oral cavity and esophagus with the active enzyme, you should swallow the product and drink it with still water.

The Berlin-Chemie company produces three types of Mezim, depending on the amount of active enzyme: Mezim forte, Mezim 10,000 and Mezim 20,000.

The most popular is forte. The other two types are used in the treatment of diseases of the gastrointestinal tract by prescription and under medical supervision.

Usual dose: 1-2 tablets three times a day before or during meals. Children can be given Mezim, including in cases of poisoning, in doses depending on age:

• up to seven years - 1 tablet 3 times a day;
• up to 12 years – 1-2 tablets 3 times a day;
• adolescents – 2000 units of pancreatin per kilogram of body weight.

In case of poisoning, Mezim can be consumed only after the gag reflexes have been relieved. The greatest effect from taking Mezim occurs 30-40 minutes after swallowing the tablet. If the attack of vomiting does not end, the medicine with the active enzyme will come out along with water and vomit without reaching the small intestine.

An adult can take eight Mezim Forte tablets per day. This is the maximum dosage that can not harm the affected body. The intake can be constant until the stomach begins to work without interruption.

Mezim for constipation (helps or harms, reviews, instructions)

Insufficient digestion and breakdown of food leads to various disorders in the body.
At the level of the gastrointestinal tract system, this is manifested by colic, spasms, strong abdominal rumbling, constipation or diarrhea. All these changes in well-being usually bother you after a meal.

Poor digestion of food negatively affects the entire body; if this disorder occurs constantly, it leads to:

• Vitamin deficiency.
• Severe weakness and poor ability to work.
• The appearance of rashes and pigmented spots on the skin.
• Drowsiness.

Digestive problems do not appear out of nowhere; in most cases, the person himself is to blame for their occurrence. A course of enzyme preparations may be required if constipation and other symptoms of bolus digestion disorders are caused by:

• Constant consumption of unhealthy food. Constipation often occurs in people who prefer to eat fatty, too salty, fried foods, smoked foods and sweets. Excessive and constant consumption of such food leads to significant disruptions in the functioning of the pancreas, liver, and stomach.
• Overeating. Even healthy food eaten in large quantities causes problems with the absorption of beneficial components.
• Poor chewing of food. Thorough chewing of all foods contributes to their better absorption and has a positive effect on the functioning of all parts of the digestive system.
• Eating too late. After about 9 pm, all metabolic processes in the body slow down, and if you eat after this time, the food will take a very long time to digest, causing heaviness, bloating, and constipation.
• Drink plenty of fluids during meals. You should consume as much water as possible, but most of it should be drunk between meals. If you drink food, an excess amount of liquid will dilute the bile, including enzymes, and this will worsen the digestion process.

If the body constantly experiences all of the listed provoking factors of poor digestion, then it may require drug treatment. It is based on preparations with enzymes, under the influence of which the digestion of food bolus will be closer to natural.

Other medicines

If you don’t want to drink expensive lactulose for a long time, use suppositories and microenemas (this most often applies to men), strong laxatives are used. They have many unwanted effects and are not suitable for long-term treatment of constipation and its symptoms.

Magnesium sulfate

Perhaps the most powerful saline laxative. A single dose (20 g) is dissolved in a glass of water. Drink the freshly prepared solution. Effect in about 2 hours.

You should not leave the house at this time. Saline laxatives work powerfully. Magnesia is good for rare constipation.

It is not recommended to use it often; it can cause dehydration and persistent diarrhea.

By using osmotic agents for several months, you can “earn” cardiovascular failure. The drugs interfere with the absorption of potassium and magnesium - this leads to heart failure.

Long-term use of saline laxatives is unacceptable in children, since disturbances in water-electrolyte metabolism can lead to dehydration.

Osmotic laxatives are able to retain water in the intestinal lumen. The stool softens.

The drugs increase the volume of intestinal contents and promote comfortable bowel movements. The drugs raise osmotic pressure by using water from the fatty tissues surrounding the intestines and plasma.

This causes a strong laxative effect of the drugs. The powerful laxative effect of salt remedies is used for poisoning.

Medicines containing bisacodyl (Dulcolax)

These can be suppositories and tablets. They help well with hemorrhoids, hypotonic and atonic constipation. If bowel movement is desired in the morning, take 1-3 bisacodyl tablets in the evening. The action develops over eight hours.

Bisacodyl is the drug of choice for the treatment of constipation accompanied by hemorrhoids and anal fissures. Drugs are used before endoscopic examination. Prescribed for various diets.

Long-term use of drugs in this group leads to dehydration and intestinal atony.

Sena preparations

among them we can highlight “Senade”, “Glacsena”, “Thick senna extract”, “Senadexin”. The initial dose is 1 tablet at night, the effect develops after 8 hours.

Disadvantages of senna preparations: intestinal colic, flatulence, addiction. Suitable only for relieving symptoms and treating occasional constipation.

Buckthorn bark, joster fruit

Gastroenterologists do not like these drugs due to the lack of strict dosing and rapid addiction.

Products containing sodium picosulfate

Among them are “Guttalax”, “Slabilen”, “Regulax” and others. They are good because they do not cause colic and chronic diarrhea. The drugs “work” at the level of the colon, increasing peristalsis.

Macrogol

The pharmacy sells Lavacol, Fortrans, Forlax.

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Drug interactions

Mezim should be taken 15 minutes after taking other medications.

The drug reduces the absorption of iron into the body and reduces the effect of medications prescribed by doctors for patients with diabetes mellitus of the second degree.

Side effects and contraindications

• A large dosage of the medicine can aggravate the patient’s condition and cause attacks of nausea, allergic reactions in the form of redness and rashes on the skin, reduce activity, depression may appear, and sleep disturbances may occur.
• In rare cases, excessive use of the drug can cause Quincke's edema and anaphylactic shock. Failure to provide professional medical care in a timely manner will result in death in 70 percent of cases.

If adverse reactions occur, you should stop taking the medication and seek advice from a specialist.

Intolerance to lactose or any other component of the drug Mezim is a contraindication to taking the medicine even during poisoning of the body. It is forbidden to drink Mezim for patients with acute pancreatitis, or with acute chronic pancreatitis.

In what cases do doctors prescribe the drug?

When overeating or eating spicy, fatty, fried foods, gastroenterologists recommend Mezim Forte, which contains the smallest amount of active ingredient, to patients. But doctors warn against its frequent use due to the development of addiction. In such cases, the pancreas simply begins to be “lazy” and produce its own enzymes. After stopping taking Mezim, a person may experience serious problems with digesting food.

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Mezim 10000 and Mezim 20000 help with dyspeptic disorders accompanying serious diseases. When malabsorption is diagnosed in patients, in the vast majority of cases such drugs are prescribed to patients for life. In combination with a gentle diet, this allows a person not to experience the painful symptoms of flatulence. Also, disruption of the gastrointestinal tract can occur in the following cases:

• Absorption of nutrients and biologically active substances occurs mainly in the stomach, small and large intestines. If part of these digestive organs was removed during a surgical operation, then a deficiency of useful compounds develops in all vital systems;
• The pancreas is not able to fully produce enzymes when it undergoes an inflammatory process or is injured by compression or bruise;
• A lack of digestive enzymes in the body occurs with pathologies of the gallbladder, as well as with blockage of the bile duct or a violation of its integrity by a large stone passing away.

All these factors that provoke digestive disorders cannot be eliminated only by taking Mezim. Diseases such as cholecystitis or pancreatitis require an integrated approach to treatment. But gastroenterologists always include in the therapeutic regimen drugs that reduce the severity of dyspepsia symptoms. Doctors prescribe Mezim to patients for flatulence that occurs against the background of all pathologies of the pancreas and gallbladder.

Nutrition for poisoning

On the first day, it is allowed to give the patient liquid. You can eat it the next day. To consolidate and normalize stool, you need to eat yesterday’s stale black bread, crackers, hard-boiled eggs, and porridges from different types of cereals. Food should be in a semi-liquid state.

It is necessary to abstain from fresh fruits and vegetables for a while. Alcohol is contraindicated. Fatty, smoked and fried foods are not recommended, so as not to provoke a new attack of vomiting or diarrhea.

• The more properly the patient eats, the faster the recovery process will take place.
• The patient should eat frequently, up to six times a day, in small portions.

Indications for the use of enzyme tablets

Mezim is a medicine intended both for the treatment of various pathologies and for the prevention of digestive disorders. Gastroenterologists recommend taking the drug before an upcoming celebration, where food that is heavy for the stomach is expected. Mezim will help quickly break down fats and carbohydrates and avoid indigestion. But the main area of ​​use of the drug is to alleviate the human condition with diseases of the digestive tract. These include:

• death of beneficial intestinal microflora, causing dyspeptic symptoms;
• chronic pancreatitis and cholecystitis;
• intestinal dyskinesia;
• impaired motility of the digestive tract;
• cystic fibrosis;
• flatulence.

Mezim is also used for constipation or diarrhea, but only if these symptoms of peristalsis disorders accompany a serious illness. The drug does not have fixative or laxative properties. Only a doctor should treat diarrhea or constipation after determining the cause of its occurrence. Mezim forte is prescribed to patients who are undergoing endoscopic examination or surgery. The drug will help to quickly cleanse the gastrointestinal tract of undigested food residues.

Use in children

Digestive disorders are often diagnosed in young children. Natural curiosity and restlessness help them explore the world, and for parents they become a source of anxiety and worry. Unwashed fruits straight from the tree, berries freshly picked from the bush are put into the mouth by hands that recently petted a stray cat or dog. It is not surprising that after a couple of days the child develops an intestinal infection. Children suffer from the following symptoms:

• bloating, rumbling and bubbling;
• diarrhea or constipation;
• nausea, vomiting;
• lack of appetite, weight loss;
• reduced motor activity.

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The use of a pharmacological drug helps to normalize the functioning of the gastrointestinal tract when taken simultaneously with medications that destroy pathogens of intestinal infections. Mezim for bloating in young children is also prescribed after eating fatty and fried foods.

Advice: “Parents should take into account one feature - when giving a child a tablet, it cannot be divided or dissolved in water. The active substance must penetrate the intestines, so the drug shell cannot be damaged.”

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Digestive disorders can be treated with Mezim during pregnancy only if you follow a gentle diet.

Poisoning prevention

To avoid poisoning, it is enough to follow simple hygiene rules: wash your hands before eating, do not eat dirty vegetables and fruits, and throw away stale food.

If you have a meeting with a large table where alcoholic drinks will be present, it is better to have a sandwich with butter or drink a glass of milk in advance. These products will help the body not to get drunk after the first drink.

Before meals, you should take a Mezim tablet so that the food is better absorbed. At the table you need to have a measure of alcohol consumed. In large quantities it is harmful to everyone. And taking Mezim will only contribute to the breakdown of alcohol, not food.

Mezim cannot relieve a poisoned person from attacks of vomiting and diarrhea. Its positive effect can influence the restoration of gastric motility, normalization of digestive processes in the body, relieve pain and heaviness in the abdomen, reduce severe gas formation, and relieve general discomfort.

Release form

You can buy Mezim at the pharmacy. Three forms of release are available to the consumer:

• Mezim : flat cylindrical tablets coated with a dense pink coating. There are 20 pieces in a package.
• Mezim Forte 10000 : pink coated tablets with a plane-parallel surface and a beveled edge. There are 10 pieces in a blister.
• Mezim 20000 : white or grayish tablets with a smooth surface. They have a specific odor; there may be a small amount of brownish inclusions on the fracture.

In the absence of chronic diseases of the digestive system, it is recommended to purchase standard Mezim Forte. It is advisable to take forms with numerical markings only as prescribed by a doctor.

Contraindications

You will have to refrain from taking Mezym Forte if:

• pancreatitis (acute or exacerbation of chronic);
• lack of lactase;
• galactose intolerance;
• some forms of diabetes;
• hypersensitivity to pancreatin;
• under three years of age.

Mezim is allowed for use in some forms of gastritis. The exception is the transition of inflammation to an ulcer. Any medications for this pathology must obtain the approval of the attending physician.

During pregnancy or breastfeeding, it is advisable to take the drug only if the potential benefit to the mother's body is stronger than the possible risk to the child. Before purchasing Mezim, be sure to check the expiration date and read the instructions.

The medicine is incompatible with alcohol . The drug stimulates the accelerated breakdown of everything that ends up in the stomach - this also applies to alcoholic beverages. This reduces the effect of intoxication. If abused, side effects may develop.