How long does it take for Duphalac to act in an adult?

Release form

The dosage form of Duphalac is syrup. It is a clear liquid. The consistency is viscous, the color is light yellow. The syrup is packaged in opaque white plastic bottles. The volume of bottles can be 200, 500 and 1000 ml. Each container comes with a measuring cup.

In addition to bottles, the syrup is packaged in foil plastic bags. This is a convenient form of release for the road and travel: you just need to squeeze a ready-made portion of the medicine into your mouth. Volume of 1 sachet – 15 ml. They are packed in cardboard boxes of 10 pieces. Instructions are included in each package.

What does the drug contain?

Duphalac's composition is simple. It contains lactulose (66.7 ml per 100 ml of the finished solution), purified water (the entire remaining volume is 33.3 ml).

The drug does not contain any other additional substances.

How the drug Duphalac helps with constipation, mechanism of action

When the syrup is taken orally, the breakdown of lactulose in the intestines begins. As a result of the decomposition process, it turns into low molecular weight organic acids. Along with Duphalac, water enters the intestines (the medicine is diluted in it), which leads to an increase in the volume of fluid in the intestines and softening of the stool.

The drug promotes the growth and development of natural beneficial intestinal microflora and reduces the number of pathogens. As a result, the activity of the organ is normalized and the process of defecation is restored.

The medicine activates intestinal motility, which facilitates the passage of feces.

Indications for use

The main purpose of Duphalac is to soften stool and treat constipation. The need for the drug arises in various conditions of the body:

• for hemorrhoids;
• in the postoperative period, especially after manipulation of the abdominal organs;
• for anal fissures.

It helps with other diseases:

• enteritis;
• dysbacteriosis (acts as a probiotic, normalizes intestinal microflora);
• salmonellosis (in the acute phase and at the carrier stage);
• liver failure;
• coma and precoma;
• putrefactive dyspepsia;
• after poisoning.

Duphalac is used as a prophylactic agent and at the stage of preparing the body for various manipulations in the intestines and other abdominal organs.

How to take for constipation

The syrup is consumed orally. Usually in the morning during meals. It is allowed to drink Duphalac in the evening, but it is believed that taking a laxative early is more productive.

The medicine can be diluted with water, juice, or mixed with fermented milk products. The syrup, which enters the stomach, is absorbed faster with food and moves more quickly to the intestines. Taking the medicine along with additional liquid improves the effect and makes it more pronounced.

One application of Duphalac in the morning may not be enough. Then it is taken again in the evening. The dosage can be divided into 2 or 3 times. It is advisable to take the syrup during the day and evening with meals.

Dosage

The amount of the drug used must be agreed with the doctor. The duration and mode of drinking syrup should be under the supervision of a specialist.

If a single dose of medication is prescribed, it should always be taken at the same time. This will allow you to quickly stabilize the process of fecal rejection and accustom the body to the regime.

On the first day, the patient is prescribed an increased dose: from 15 to 45 ml per day. It can be taken at one time or divided into several. The question of the regimen is decided individually with the doctor.

On the second and subsequent days, the dosage is reduced: 10-30 ml/day. You can limit yourself to taking the entire daily dose of syrup once or divide it into 2-3 times.

Important condition : the patient must consume a sufficient amount of water: 1.5-2 l/day.

Rules for taking medication

Duphalac, like any pharmacological drug, has specific uses. The general admission rules are the same for children and adults. Is it better to take Duphalac in the morning or evening? The laxative is prescribed in doses appropriate to age. According to the instructions, the medicine should be taken once a day, during meals, in the morning .

Taking it in the morning helps ensure regular bowel movements. Violation of the regime will cause difficulties in the functioning of the intestines. Can I drink Duphalac in the evening? At night, the intestines contract more than during the day under the influence of the vagus nerve. Using the medicine in the evening is not advisable , as this will further enhance intestinal motility and cause discomfort in the abdomen. Therefore, doctors do not recommend drinking Duphalac at night. Children are also advised to use the medicine in the morning and afternoon (during meals, 1 time per day).

Duphalac for the elderly

Constipation in the elderly is several times more common than in young people. This is due to several factors.

Firstly, with age, due to natural reasons, intestinal motility weakens. Secondly, older people lead a less active lifestyle, and external (muscular) stimulation of the intestines weakens.

Fecal masses move worse, more often get stuck, traffic jams occur, and the processes of rotting and fermentation are activated in the intestines..

As a result, half of people over 60 regularly experience constipation. Among those over 75 years of age, the percentage increases to 80-85%.

Duphalac will help solve a delicate problem regardless of age. The drug can be taken by elderly patients. The dosage remains the same: first 15-45 ml, from the second day - 15-30 ml.

How long can you drink Duphalac without a break?

Duphalac is a remedy that has a pronounced laxative effect. It is prescribed to adults and children. For treatment to be effective, you need to know how to take Duphalac for constipation.

Release form

The dosage form of Duphalac is syrup. It is a clear liquid. The consistency is viscous, the color is light yellow. The syrup is packaged in opaque white plastic bottles. The volume of bottles can be 200, 500 and 1000 ml. Each container comes with a measuring cup.

In addition to bottles, the syrup is packaged in foil plastic bags. This is a convenient form of release for the road and travel: you just need to squeeze a ready-made portion of the medicine into your mouth. Volume of 1 sachet – 15 ml. They are packed in cardboard boxes of 10 pieces. Instructions are included in each package.

What does the drug contain?

Duphalac's composition is simple. It contains lactulose (66.7 ml per 100 ml of the finished solution), purified water (the entire remaining volume is 33.3 ml).

The drug does not contain any other additional substances.

How the drug Duphalac helps with constipation, mechanism of action

When the syrup is taken orally, the breakdown of lactulose in the intestines begins. As a result of the decomposition process, it turns into low molecular weight organic acids. Along with Duphalac, water enters the intestines (the medicine is diluted in it), which leads to an increase in the volume of fluid in the intestines and softening of the stool.

The drug promotes the growth and development of natural beneficial intestinal microflora and reduces the number of pathogens. As a result, the activity of the organ is normalized and the process of defecation is restored.

The medicine activates intestinal motility, which facilitates the passage of feces.

Indications for use

The main purpose of Duphalac is to soften stool and treat constipation. The need for the drug arises in various conditions of the body:

• for hemorrhoids;
• in the postoperative period, especially after manipulation of the abdominal organs;
• for anal fissures.

It helps with other diseases:

• enteritis;
• dysbacteriosis (acts as a probiotic, normalizes intestinal microflora);
• salmonellosis (in the acute phase and at the carrier stage);
• liver failure;
• coma and precoma;
• putrefactive dyspepsia;
• after poisoning.

Duphalac is used as a prophylactic agent and at the stage of preparing the body for various manipulations in the intestines and other abdominal organs.

How to take for constipation

The syrup is consumed orally. Usually in the morning during meals. It is allowed to drink Duphalac in the evening, but it is believed that taking a laxative early is more productive.

The medicine can be diluted with water, juice, or mixed with fermented milk products. The syrup, which enters the stomach, is absorbed faster with food and moves more quickly to the intestines. Taking the medicine along with additional liquid improves the effect and makes it more pronounced.

One application of Duphalac in the morning may not be enough. Then it is taken again in the evening. The dosage can be divided into 2 or 3 times. It is advisable to take the syrup during the day and evening with meals.

Dosage

The amount of the drug used must be agreed with the doctor. The duration and mode of drinking syrup should be under the supervision of a specialist.

If a single dose of medication is prescribed, it should always be taken at the same time. This will allow you to quickly stabilize the process of fecal rejection and accustom the body to the regime.

On the first day, the patient is prescribed an increased dose: from 15 to 45 ml per day. It can be taken at one time or divided into several. The question of the regimen is decided individually with the doctor.

On the second and subsequent days, the dosage is reduced: 10-30 ml/day. You can limit yourself to taking the entire daily dose of syrup once or divide it into 2-3 times.

Important condition : the patient must consume a sufficient amount of water: 1.5-2 l/day.

Duphalac for the elderly

Constipation in the elderly is several times more common than in young people. This is due to several factors.

Firstly, with age, due to natural reasons, intestinal motility weakens. Secondly, older people lead a less active lifestyle, and external (muscular) stimulation of the intestines weakens.

Fecal masses move worse, more often get stuck, traffic jams occur, and the processes of rotting and fermentation are activated in the intestines..

As a result, half of people over 60 regularly experience constipation. Among those over 75 years of age, the percentage increases to 80-85%.

Duphalac will help solve a delicate problem regardless of age. The drug can be taken by elderly patients. The dosage remains the same: first 15-45 ml, from the second day - 15-30 ml.

Use of the drug in children (including infants) for constipation

Duphalac is allowed to be given to children from birth. The medicine can be offered to infants undiluted or with breast milk or baby food. The drug is given in the morning immediately after sleep or feeding. The daily dose for newborns is 5 ml.

Source: https://za-dolgoletie.ru/info/skolko-mozhno-pit-djufalak-bez-pereryva/

Use during pregnancy and breastfeeding

Constipation becomes more frequent during pregnancy. This is due to many factors: the uterus grows, contractile muscles lose tone, intestinal microflora changes, etc. Often, changing the diet does not cope with the problem, and there is a need to prescribe medications.

Duphalac is allowed to be taken during pregnancy and lactation. This is one of the harmless remedies that have no harmful effects on the body of the expectant mother and child. The syrup softens the stool, making it easier to pass, but the body does not leave the necessary minerals.

Duphalac is allowed to be used during lactation. It has a beneficial effect on the mother's body. It is not excreted in breast milk and therefore has no direct effect on the baby. How to take the medicine? It is prescribed to pregnant and lactating women in the same way as to all other adults.

Features and nuances

The drug is allowed to be taken by children of any age. For newborn babies, the use of the medicine must be combined with correction of the mother's diet. Parents need to know how to drink Duphalac correctly for children.

For newborn babies and children under one year of age, the initial and maintenance daily dose is 5 ml; For small children from one year to six years, the initial and maintenance daily dose is 5-10 ml; For schoolchildren aged 7 to 14 years, the initial daily dose is 15 ml, maintenance - from 10 to 15 ml;

Pregnant

The medicine is approved for use by both pregnant girls and nursing mothers. Constipation during pregnancy is very common. The fact is that the same muscles are responsible for the contraction of the intestines and the uterus in which the child develops. Therefore, it is not always possible to eliminate constipation through diet alone.

This drug is one of the most harmless. It easily softens stool and promotes successful bowel movement. Does not remove minerals and salts needed by the body.

The drug does not have a negative effect on the mother's body. And when feeding, it has a beneficial effect on the child’s body.

It will be very useful for pregnant women to watch the following video

Elderly

According to official statistics, older people are more susceptible to constipation than ordinary adults.

The fact is that intestinal motility weakens. Feces get stuck in the bends of the intestines, causing rotting and fermentation. In people over sixty years of age, constipation occurs in 50% of cases. In patients over 75 years of age, constipation occurs in 85% of cases.

How long does the treatment last?

The medicine Duphalac acts very mildly, so to achieve a sustainable effect you will have to take it for a long time.

The manufacturer indicates that in case of problems with fecal rejection, the course of treatment should be at least a month. Reception for prevention or in preparation for any manipulations with the intestines lasts from 3 to 7 days.

For newborns, the period of admission ranges from 1 to 3 weeks. The final option is determined by the doctor depending on the purpose of the appointment.

How long can Duphalac be used?

The drug is not addictive; take the syrup until intestinal activity is restored. It takes several weeks to regulate excretory function.

During pregnancy and breastfeeding, the duration of use is not limited. However, observation by a specialist is necessary, since the female body becomes more susceptible and is able to react unconventionally to taking the drug.

Duphalac is not excreted in breast milk, so you don’t have to worry about the baby’s health.

Newborns are not given clear boundaries for taking the drug. With a long course, you need to be observed by a pediatrician.

How to quickly expect the effect?

The speed of obtaining the effect depends on several factors: the amount of the drug taken, the disease and its severity. The average time it takes to cleanse the intestines is 4 to 12 hours.

Such a long period is due to the fact that Duphalac has a mild effect and does not have an immediate effect on intestinal function..

In some cases, the patient's age and health status play a role. Thus, in older people the processes proceed more slowly, so the result appears within a day. In a child, everything happens faster, so the intestines can clear out even a couple of hours after taking the initial dosage.

Instructions for Duphalac®

Instructions for use of the medicinal product for medical use DUPHALAC® (DUPHALAC®)

Registration number : P N011717/02 Trade name : Duphalac® International nonproprietary name : lactulose Chemical name : 4-O-ß-D-galactopyranosyl-D-fructose Dosage form : syrup Composition : 100 ml of solution contains:

active substance: lactulose 66.7 g;

excipient: purified water up to 100 ml.

Description : transparent viscous liquid from colorless to light yellow with a brownish tint. Pharmacotherapeutic group : laxative. ATX code : A06AD11

Pharmacological properties

Pharmacodynamics Has a hyperosmotic laxative effect, stimulates intestinal motility, improves the absorption of phosphates and Ca2+ salts, and promotes the excretion of ammonium ions.

Lactulose is broken down by the intestinal flora of the colon into low molecular weight organic acids, which leads to a decrease in pH and an increase in osmotic pressure and, as a consequence, an increase in the volume of intestinal contents. These effects stimulate intestinal motility and affect stool consistency.

As a result, the physiological rhythm of colon emptying is restored.

In hepatic encephalopathy, the effect is attributed to suppression of proteolytic bacteria by increasing the number of acidophilic bacteria (eg, lactobacilli), conversion of ammonia to ionic form by acidification of colonic contents, bowel emptying due to decreased colonic pH and osmotic effects, and reduction of nitrogen-containing toxic substances by stimulation of bacteria that utilize ammonia for bacterial protein synthesis. Lactulose as a prebiotic substance enhances the growth of beneficial bacteria such as bifidobacteria and lactobacilli, while inhibiting the growth of potentially pathogenic bacteria such as Clostridium and Escherichia coli, resulting in a more favorable balance of intestinal flora.

Pharmacokinetics Absorption is low. After ingestion, it reaches the large intestine unchanged, where it is broken down by intestinal flora. Completely metabolized at doses up to 40-75 ml. When used in higher doses, it is partially excreted unchanged.

Indications for use – Constipation: regulation of the physiological rhythm of colon emptying. – Softening of stool for medical purposes (hemorrhoids, conditions after surgery on the colon and anus).

– Hepatic encephalopathy in adults: treatment and prevention of hepatic coma or precoma.

Contraindications – galactosemia; – obstruction, perforation or risk of perforation of the gastrointestinal tract; – hypersensitivity to any component of the drug;

– galactose or fructose intolerance, lactase deficiency or glucose-galactose malabsorption.

With caution - undiagnosed rectal bleeding;

– colostomy, ileostomy.

Use during pregnancy and breastfeeding3 No effect on the fetus or infant is expected, since the systemic exposure of lactulose to a pregnant or lactating woman is negligible.

Duphalac® can be prescribed during pregnancy and breastfeeding. No effect on reproductive function is expected, because Systemic exposure to lactulose is negligible.

Method of administration and dosage The drug is intended for oral administration. Lactulose solution can be taken either diluted or undiluted. It is necessary to immediately swallow the single dose taken without holding it in the mouth. All dosages must be selected individually.

If a single daily dose is prescribed, it must be taken at the same time, for example, during breakfast. During laxative therapy, it is recommended to take a sufficient amount of fluid (1.5-2 liters, equal to 6-8 glasses) per day.

To accurately dose the drug in vials, use the included measuring cup. When using the drug in sachets, you must tear off the corner of the sachet and immediately take the contents.

Dosage for the treatment of constipation or for softening stool for medical purposes The daily dose of lactulose can be taken once or divided into two using a measuring cup.

After a few days, the initial dose may be adjusted to a maintenance dose depending on the response to the drug. The laxative effect may appear 2-3 days after starting to take the drug.

Age Initial daily dose Maintenance daily dose

If the maintenance daily dose is less than 15 ml, as well as for precise dosing in children under 7 years of age, it is recommended to use the drug in vials.

Dose for the treatment of hepatic encephalopathy (adults) Initial dose: 3-4 times a day, 30-45 ml. Then they switch to an individually selected maintenance dose so that soft stools are produced 2-3 times a day maximum.

The safety and effectiveness of the drug in children (under 18 years of age) with hepatic encephalopathy has not been established due to a lack of data.

Elderly patients and patients with renal or hepatic insufficiency There are no special dosage recommendations, since the systemic exposure to lactulose is negligible.

Side effects In the first days of taking lactulose, flatulence may occur. As a rule, it disappears after a few days.

If high doses are used for a long time in the treatment of hepatic encephalopathy, the patient may develop water and electrolyte imbalance due to diarrhea.

Gastrointestinal disorders Very common (≥1/10): diarrhea. Often (≥1/100,

Source: https://duphalac.ru/instrukciya/duphalac/

Use of the drug to prevent constipation

The medicine is also used as a prophylactic agent. It is prescribed to prepare the body for various manipulations on the intestines.

The dosage is increased to 100-150 ml. The maximum period during which it is allowed to drink syrup in such doses is 7 days. Usually the preparation period is 1-2 days. The effect is enhanced when the medication is combined with cleansing enemas.

Attention! You cannot prescribe the drug and prescribe the dosage yourself. Only a doctor can do this correctly. Otherwise, side effects may develop and symptoms of overdose may appear.

Possible side effects

Duphalac is a fairly harmless medicine, but it has some side effects. They usually appear in the first days of taking the drug, and this is considered normal. If symptoms persist after 3-4 days, you should consult a doctor. It may be necessary to reduce the dosage or completely abandon the syrup.

Usually a side effect occurs when choosing the wrong dosage. Patients are concerned about:

• increased gas formation;
• nausea;
• abdominal pain;
• headache;
• vomit;
• disturbance of water-electrolyte balance (with prolonged overdose, minerals, for example, calcium salts, are washed out of the body).

Overdose

In case of overdose, diarrhea occurs, accompanied by abdominal pain. Goes away on its own after discontinuation of the drug.

With prolonged overdose, the water-electrolyte balance is disrupted due to incessant diarrhea: the body loses calcium and other minerals. You can get rid of the disorder by taking electrolyte solutions.

What are the contraindications?

There are a number of cases when taking the drug is contraindicated. It should not be prescribed to patients with diseases such as:

• acute intestinal obstruction;
• colostomy;
• galactosemia;
• lactulose and lactose intolerance.

Duphalac contains traces of lactose, fructose and other simple sugars. The syrup should be taken with caution, as prescribed by a doctor and under supervision when:

It is recommended to refrain from taking Duphalac if:

• intestinal bleeding;
• ileostomy.

Additional instructions

Duphalac does not reduce concentration, ability to drive vehicles or complex mechanisms, so it can be taken by drivers, technicians and mechanics.

The drug is poorly compatible with alcohol, so you should avoid drinking alcohol during the treatment period.

The drug does not affect the reproductive function of patients.

Can I buy the drug without a prescription?

Duphalac is available without a doctor's prescription. To purchase, just tell the pharmacist the name of the medicine and the required volume.

How to store the drug

The product must be stored in a dark place. It should not be exposed to direct sunlight. The storage location should be cool: maximum temperature - 25 degrees, minimum - zero. Freezing Duphalac is unacceptable.

The product should be in a dry place so that no foreign liquid gets into it. It should be kept away from children and pets.

Duphalac is a fairly effective remedy for such a delicate issue as constipation. But if stool retention is chronic, then long-term use of the drug is necessary. In such situations, a person often asks the question: “How long can adults take Duphalac?”

Description of the drug

Duphalac is a drug whose therapeutic effect is achieved due to lactulose, which is part of it. This substance is a natural product because... it is obtained from whey.

The therapeutic effect is achieved by increasing the osmotic pressure in the intestinal lumen and reducing its acidity. As a result, water molecules are attracted, stool is liquefied and intestinal motility is stimulated.

Is Duphalac addictive in adults? To answer this question, you need to understand what properties the drug has:

• The drug has a natural composition, because in addition to lactulose, Duphalac contains purified water;
• Duphalac does not irritate the intestinal mucosa;
• The drug does not tend to accumulate in the body and negatively affect the liver and kidneys, because excreted by digestion by intestinal bacteria;
• Duphalac does not disturb the intestinal microflora, but rather helps it become populated with beneficial microorganisms, suppressing the growth of pathogenic bacteria;
• The drug acts only locally in the intestines, without entering the bloodstream and other body fluids.

So is Duphalac addictive or not? Unlike enemas, which reduce the natural reflex to defecation, a drug based on lactulose is not addictive. This means that even after stopping the drug, a person will be able to independently perform a bowel movement without the use of additional methods.

How to take Duphalac - instructions for children and adults

Nowadays, buying an effective remedy that can help get rid of constipation is quite simple.
After all, all you need to do is go to any pharmacy and simply pay for the medicine. But in order to really get the desired effect from a laxative, you should first become familiar with the mechanism of its action and the rules of administration in order to accurately get rid of the unpleasant manifestation.

Quite often, for those patients who complain of difficulty in bowel movements, the attending doctor prescribes laxative medications. The latter are based on lactulose, for example, the well-known Duphalac.

Everyone should know how to take Duphalac for constipation in order for the medication to act effectively, and before starting treatment therapy.

And since the process of taking a laxative is quite simple, everyone, without exception, can remember the correct regimen.

Mechanism of action of the drug

The medicine has a syrupy consistency, and its shade can be either light yellow or completely transparent. When treated with Duphalac, intestinal motility improves, and both calcium and phosphates begin to be absorbed better. After the end of treatment, ammonium ions begin to be freely excreted from the patient’s body.

In simple words, the mechanism of action of laxative syrup prescribed to adults who are concerned about constipation can be said this way - the medicinal syrup acts by changing the amount of fluid present in the cavity of the large intestine. Liquid is formed in the intestines due to an increase in the amount of acids of organic origin, which are formed during the breakdown of the main active component of the medicinal syrup - lactulose.

The process of lactulose breakdown is facilitated by beneficial microorganisms, whose habitat is the gastrointestinal tract.

This is exactly how the syrup called Duphalac works, prescribed to adults for constipation. However, you should definitely know that the desired effect will not be obtained immediately after taking the drug orally, but only after 2 days, while adhering to the simple rules for taking the medicinal syrup.

Brief description of the drug

Duphalac is a medicine that has a laxative effect on the body. The drug has a natural composition, which includes lactulose and water. Therefore, taking a laxative is allowed for women during pregnancy and lactation, as well as for newborn children.

The drug is prescribed for the treatment of constipation, dysbacteriosis, hepatic encephalopathy, and salmonellosis.

Before answering the question of whether you can drink Duphalac at night, you should understand what properties the laxative has.

• Lactulose increases osmotic pressure in the intestines, reducing its acidity;
• The drug attracts water molecules, thereby liquefying feces;
• Thanks to the breakdown of lactulose, the amount of feces increases and intestinal motility is stimulated;
• The laxative helps calcium salts and phosphates to be absorbed.
• Duphalac normalizes intestinal microflora;
• The drug helps to neutralize and remove harmful substances and toxins from the body, including ammonia;
• The laxative does not irritate the intestinal mucosa, is not addictive and is not absorbed into the blood, acting only locally.

Rules for taking laxatives

It is very important in medical therapy to know how to take laxative syrup correctly, when is it better - in the morning or in the evening, before meals or after meals? Let's look at these questions in order:

When is it better to take syrup in the morning or evening? The answer to this question can be found in the instructions for the drug, which clearly states that taking the syrup in the morning will give the best effect.

Doctors also completely agree with this statement, explaining this point as follows - morning food, when it enters an as yet unfilled stomach, provokes the development of the gastrocolic reflex.

That is, when the walls of the stomach are stretched due to food entering the organ, gastrin begins to be released, quite abundantly, and so-called peristaltic waves begin to be launched inside the intestines.

To avoid such manifestations, doctors recommend drinking a glass of purified drinking water at room temperature immediately after waking up. According to experts, bowel movement after eating the first breakfast is considered the most beneficial for the health of both adults and children.

For the first dose of Duphalac for adults, it is enough to use 30-45 ml of syrup; for subsequent doses, the amount of the medicinal composition should not exceed 25 ml.

When is the best time to take Duphalac?

The instructions say that it is better to take Duphalac in the morning during breakfast, and not at night. This is explained by the fact that food after sleep, entering an empty stomach, forms a gastrocolic reflex, which does not occur when taking a laxative at night.

As a result, food taken on an empty stomach greatly stretches the walls of the stomach, stimulating peristaltic waves and starting the process of defecation. Thanks to this property, the effectiveness of the drug increases and the therapeutic effect of the drug occurs faster.

But is it possible to take a laxative at night? To answer this question, you need to find out after what time the drug begins to work.

The therapeutic effect can occur within 2-48 hours. This time depends on the individual rate of transformation of chemicals.

For example, in people with high speed, the effect occurs much faster. Therefore, in order to determine the time, it is better to take the first dose in the morning.

In the case when the therapeutic effect occurs after 2-4 hours, it is better not to take the drug at night.

If a person notices that the effect occurs only after 8-12 hours, then it is permissible to take Duphalac at night. In this case, a person will be able to empty his bowels without problems in the morning.

If the doctor has prescribed multiple doses of the drug, the laxative is taken both in the morning and at night.

It is best to take a laxative before or after meals

When is the best time to take laxative syrup - before or after meals? According to doctors, Duphalac should be taken with meals to achieve maximum effect. If necessary, the dose of the laxative is diluted with water or any fruit drink. This technique provides several advantages:

• medication combined with food penetrates the surface layer of the colon much faster;
• syrup diluted in a sufficient amount of liquid improves the laxative characteristics of the medication in question.

If the morning dose is not enough to normalize stool, it is allowed to increase the dosage, but only with the permission of the attending physician.

Source: https://mmc-optima.ru/drugoe/dyufalak-pered-edoj-ili-posle.html

How long can I take it?

The exact duration of treatment, which will not cause negative consequences, can be determined by your doctor. He will assess the condition of an adult patient, identify the type and duration of the disease, the presence or absence of contraindications and concomitant diseases.

Lactulose begins to act only in the large intestine, so the therapeutic effect for constipation is achieved after 12-48 hours. The exact time depends on the individual characteristics of the body. Due to the gradual and long onset of the therapeutic effect, the drug is best taken in courses. Therefore, it is necessary to drink Duphalac for the treatment of constipation for at least 14 days. In this way, you can achieve a lasting and long-lasting effect.

Duphalac is mainly prescribed for the treatment of:

• Hepatic encephalopathy. Start drinking the drug 30-45 ml/3 times a day. Then the body’s response to the drug is assessed and an individual dosage is selected. The course of treatment for this disease is long, ranging from 3 months or more. If the course lasts more than six months, then it is necessary to monitor blood parameters for the level of electrolytes;
• For dysbacteriosis, the course of treatment with an amount of 10 ml of the drug/day is 3 weeks or more. After all, lactulose does not act immediately, but gradually, populating the intestines with microorganisms;
• Chronic constipation. In this case, 15-45 ml of the drug is prescribed at the very beginning of treatment, and after the onset of the effect, maintenance therapy is taken in the amount of 15-30 ml. The course of treatment for constipation with Duphalac ranges from 3 weeks to 3-4 months . It is believed that during this time the intestines are populated with beneficial bacteria and stool becomes regular. In case of rare constipation, it is permissible to take Duphalac once.

From all of the above, we can conclude that in the absence of contraindications and side effects, Duphalac can be taken for up to six months or even longer.

What is Duphalac?

Duphalac is an original drug whose active ingredient is lactulose. Lactulose is a disaccharide, i.e. a simple carbohydrate that is not absorbed or digested, because there are no enzymes in the human body that would break down lactulose. Therefore, it passes to the large intestine unchanged. And here lactulose serves as a nutrient medium for its own bifidobacteria and lactobacilli.

What is Duphalac made from?

Duphalac is made from whey, which is obtained during the cheese production process.

How does Duphalac work?

Duphalac enhances the physiological mechanisms of bowel movement and promotes the growth of its own beneficial microflora in it. Thus, it restores normal bowel function.

Duphalac is not absorbed from the gastrointestinal tract and enters the large intestine unchanged. Here it is an ideal nutrient medium for the intestinal’s own bifidobacteria and lactobacilli. As a result of their breakdown of Duphalac, organic acids are formed, which help increase intestinal contents and stimulate intestinal motility, accelerating bowel movements. In addition, being a food for its own bifidobacteria and lactobacilli, Duphalac stimulates the rapid growth of beneficial microflora. This helps to normalize the intestinal microflora.

How to take Duphalac?

Duphalac can be used from the first days of a child's life. The dosage of Duphalac is selected individually and depends on the age of the patient.

The initial dosage of Duphalac is used for 3-4 days, then it is recommended to switch to a maintenance dosage, which is half the initial one. And continue treatment for 2-3 weeks.

Duphalac is taken once a day in the morning after breakfast. Duphalac can be taken pure or diluted in any liquid (water, juice, tea, kefir)

How long can you take Duphalac?

Duphalac can be taken for as long as necessary.

Why is Duphalac recommended to be taken in the morning?

This is due to the fact that the rate of onset of the laxative effect while taking Duphalac varies from person to person. It can be 2 hours, or maybe 12 or even 24. It depends on the condition of the intestines and the sensitivity of the intestines to lactulose. Therefore, it is recommended to always start taking Duphalac in the morning. This will help you navigate in the future, based on the time of onset of the effect. If your laxative effect always occurs after an average of 6-8 hours, then you can safely take Duphalac at night, and then by the morning you will have normal bowel movements.

Why is Duphalac recommended to be taken in courses lasting up to 1 month?

Description of the drug

Duphalac is a mild laxative, the effect of which occurs by lowering the level of acidity in the intestine and increasing the osmotic pressure of its lumen. This effect is achieved thanks to the main active ingredient – ​​lactulose.

In addition to lactulose, Duphalac contains a small amount of purified water as an excipient. Thanks to this composition, the drug is prescribed even to pregnant and lactating women, as well as newborn children.

Properties of Duphalac:

• Increases osmotic pressure in the intestinal lumen;
• Reduces intestinal acidity;
• Liquefies stool;
• The drug does not accumulate in the body and, unlike an enema, is not addictive, so you can take Duphalac for long courses;
• Removes harmful substances from the body, while leaving useful ones in the body;
• Helps absorb calcium and phosphates into the body;
• Neutralizes the dangerous toxin Ammonia, which is formed during hepatic encephalopathy;
• Lactulose enters the intestines unchanged and begins to break down without entering the bloodstream. Therefore, the drug does not have a negative effect on the organs and systems of the body;
• Duphalac inhibits the growth of pathogenic microorganisms, stimulating the production of beneficial intestinal bacteria;
• It does not irritate the intestinal mucosa, therefore it is suitable for long-term use, and even for the prevention of constipation for both adults and small children.

Composition and description

100 ml of this drug contains 66.7 grams of lactulose, which is the active component of the drug. Water is used as an auxiliary ingredient. For the specified amount of lactulose, exactly enough water is added to bring the volume to 100 ml.

The product is sold in bottles and plastic bags for one dose. The volume of the bottle can be 0.2; 0.5 and 1 l. It comes with a measuring cup. One dose is sold in a 15 ml plastic bag. Also on sale are plastic bags that contain 800 ml of medicine.

The drug is suitable for use by adults and children. The action of the drug is as follows:

• hyperosmotic laxative;
• the medicine stimulates intestinal peristalsis;
• improves the excretion of ammonium ions;
• promotes the absorption of Ca2+ salts and phosphates.

During the breakdown of lactulose in the colon, it breaks down into low molecular weight acids. This leads to a decrease in acidity, an increase in osmotic pressure and an increase in the amount of intestinal contents. Thanks to these effects, intestinal motility is stimulated. In addition, stool consistency improves, which helps relieve constipation and restore the normal rhythm of colon emptying.

The effectiveness of the drug in hepatic coma and encephalopathy is explained by an increase in the number of acidophilic bacteria and suppression of the number of proteolytic bacteria. As the contents of the large intestine become acidified, ammonia becomes ionic. In addition, in the listed pathologies, Duphalac stimulates bacteria that reduce the concentration of nitrogen-containing toxins and utilize ammonia for the purpose of protein synthesis.

The drug has low absorption. It is practically not absorbed from the intestines and reaches the colon, where it is broken down by intestinal flora. When using the medicine in a dose of 45-70 milliliters, it is completely metabolized. If the specified dosage is exceeded, part of the medication is excreted unchanged.

Important! This medication is approved for use during pregnancy and breastfeeding.

Dosage

How often you can take Duphalac is decided by your doctor on an individual basis . The specialist assesses the condition, duration of the disease, identifies the presence of concomitant diseases and decides how many days a particular person can take the drug.

Since lactulose begins to act only in the human large intestine, the therapeutic effect has to wait a long time. On average, it occurs within 12-24 hours. Sometimes the onset of the effect may be delayed and occur after 48 hours. If the effect of the drug is not observed within 3 days, then you need to inform your doctor.

The dosage depends on the age and type of disease:

• To treat constipation, adults are prescribed 15-45 ml of the drug. Further, after the onset of the therapeutic effect, the dosage is reduced to 15-30 ml of Duphalac. Children under one year of age are prescribed up to 5 ml of the drug. A child from one to 7 years of age is prescribed 5-10 ml of the drug. A child from 7 to 14 years old is prescribed 10-15 ml in the initial stages, and 10 ml/day as maintenance therapy;
• For the treatment of salmonellosis and shigellosis, take 15 ml/3 times a day for the first 2 weeks, then after a 7-day break, take the same amount of the drug, but only 5 times a day;
• For the treatment of dysbiosis from birth to 12 months, 1-3 ml of Duphalac is prescribed, from 12 months to 3 years, 3 ml of the drug is prescribed. At the age of 4-7 years, take 5 ml of the drug. Children over 7 years of age and adults are prescribed 10 ml of the drug/day;
• When treating hepatic encephalopathy, 30-45 ml of the drug/3 times a day is prescribed at the initial stages, and then an individual maintenance dosage of Duphalac is selected.

Duphalac - instructions for use, contraindications

03.26.2019 · : 0 · Reading time: 6 min · Views:

Every third person in Russia reported symptoms of constipation. This is a delicate problem, and people are often embarrassed to consult a doctor with such a complaint.

Constipation is not always a consequence of any disease, and you can cope with this unpleasant ailment on your own. It is important to carefully study which drug is suitable, safe and effective.

Duphalac is the latest generation osmotic laxative.

Advantages of Duphalac

Delayed and difficult bowel movements not only worsen general well-being and affect the quality of life. People who regularly suffer from this problem have an increased risk of developing colorectal cancer. To avoid such a dangerous complication, it is important to use modern means included in the clinical recommendations of gastroenterologists.

The most widely known are stimulant laxatives, for example, Bisacodyl, Regulax, herbal preparations of senna and buckthorn, castor oil. These are old-generation drugs that have a number of undesirable effects:

• development of the opposite condition - diarrhea;

• Accompanying the intake with abdominal discomfort (unpleasant gurgling, cramping pain);

• disruption of the functioning of local nerve nodes;

• addiction with the subsequent development of the so-called “lazy bowel syndrome”.

Herbal preparations - senna leaf and buckthorn bark - also contain anthraglycosides. These insidious substances are genotoxic and can themselves cause the development of intestinal cancer.

The laxative Duphalac today is one of the first choice in the treatment of constipation. Unlike stimulant laxatives, this syrup works very gently, softens and breaks down hardened stool without developing painful urges or diarrhea.

Duphalac syrup, in addition to its main effect, has a beneficial probiotic effect on the intestinal microflora.

The main substance of the drug - lactulose - not only gently laxatives, but also acts as fertile soil for the growth and reproduction of beneficial microbiota (Bifidobacterium and Lactobacterium).

A normal level of “good” bacteria promotes proper digestion and regular, comfortable bowel movements.

Thanks to these properties, long-term use of Duphalac syrup is allowed, unlike most laxatives. It is so safe that it is prescribed for the treatment of situational constipation even for pregnant women, nursing mothers and children from birth.

Lactulose is a derivative of milk sugar. This is due to the probiotic effect of the drug and its pleasant taste.

One of the undoubted advantages of the Duphalac laxative is its minimal systemic effect. It has virtually no general effects on the body as a whole, actively working directly in the intestines.

Many medications require dosage adjustments for people with severe liver and/or kidney disease and the elderly. Due to the absence of a systemic effect on the body, the dose of lactulose for such patients is not reduced. However, if you have serious health conditions, you should consult your doctor before taking any medications.

Instructions for use of Duphalac syrup

Depending on the situation in which the drug is used, you can purchase a convenient release form. There are several of them:

• Single-use sachets of 15 ml - the form is suitable for sudden constipation associated, for example, with a flaw in the diet. You can even buy at the pharmacy not the whole pack of 10 pieces, but 1 - 3 sachets to normalize stool. Convenient and inexpensive.
• A 200 ml polymer bottle is a small bottle for those who need a short course of use, for example, to cleanse the intestines before a medical examination.
• 500 ml bottle - for those who have been prescribed a long course by a doctor, for example, for chronic constipation in the elderly or in the case of hepatic encephalopathy.
• The largest bottle is 1 liter. Also suitable for long courses, but will cost even more in terms of price.

Thus, for each specific situation, you can choose the appropriate commercial form of syrup, while obtaining the desired effect and saving money.

The laxative has a pleasant sweet taste, but some people do not really like sweet syrups. In such a situation, the instructions for use allow diluting the drug in water.

Application procedure

A single dose should be swallowed immediately - do not drink the syrup in small sips or hold it in your mouth for a long time.

The daily dose depends on the reason for use, age, weight and duration of the course. The daily volume of the drug can be taken at a time, or can be divided into two doses.

Regardless of whether the syrup is taken once a day or in two doses, the same time of application must be observed. For example, every day at 12 noon, or, in the case of splitting the dose, at 8 am and 8 pm.

Be sure to monitor the amount of liquid consumed. The mechanism of action of lactulose is such that during therapy it is necessary to constantly drink a sufficient amount of water - at least 1.5 - 2 liters per day.

If you use the packaged form, Duphalac should be taken immediately after opening the package. An opened bag cannot be stored.

The syrup in bottles must be accurately dosed using a special measuring container included in the kit. The marks on it are called menisci. It is important to know that the poured volume must be assessed by the lower edge of the meniscus.

When treating with a course, the dose is higher in the first days, and subsequently it is reduced to maintenance.

How long does it take for Duphalac to work?

The laxative effect develops very smoothly. The result may occur within 24 hours after the first dose, but the effect is allowed to occur within 2-3 days of therapy.

How to calculate the dosage?

The main indicator for calculating the dose is age, but weight is also important. For example, the instructions state that a starting dose of 15–45 ml per day is indicated for adolescents over 15 years of age and adults. It is clear that a thin fifteen-year-old girl will take 15 ml, but an obese middle-aged man will need 45 ml.

At the same time, a teenager’s metabolism is more active, and there is no point in splitting the daily dose into two doses. Whereas in an older person, especially if overweight, the metabolism will be slower. Here it is advisable to divide 45 ml into morning and evening doses for a more optimal and faster effect. Such nuances should be taken into account when determining the dose.

Doses by age:

• babies under 1 year old - the daily volume should not exceed 5 ml. Typically, pediatricians prescribe 2–2.5 ml twice a day;

• Children from one to six years old are given 5-10 ml per day. In the case of a course of treatment, the dose is higher for the first 3–5 days, then reduced;

• children aged 7 - 14 years old receive 10 - 15 ml per day. During the course of therapy, the first days give 15 ml/day, then reduce the volume to 10 ml/day;

• Teenagers from 15 years of age and adults usually consume 15 - 30 ml per day. When the form is bagged, it is 1 − 2 sachets. If a course of treatment is intended, in the first days the dose can reach 45 ml (or 3 sachets) per day.

In what other cases is Duphalac prescribed?

There are cases when Duphalac is used not for constipation, but to soften stool for medical reasons. For example, people suffering from various forms of hemorrhoids, especially with cracks in the intestinal walls accompanying this disease. This is also reasonable after operations in the anorectal area, colon or rectum.

In these situations, it is very important that the stool is soft, plastic, and saturated with liquid, since hard stool will cause additional trauma to the mucous membrane.

When should you not take Duphalac?

• Lactulose, like other milk sugars, is prohibited for people with a hereditary disorder of the transition of galactose to glucose during metabolism.
• The drug is contraindicated in cases of lactase deficiency, fructose and/or galactose intolerance.
• Do not use any laxatives for intestinal obstruction or other gastrointestinal disasters (perforation or risk of perforation of the walls of the digestive tract).

• Duphalac should be used with caution in case of rectal bleeding of unknown origin. As prescribed by the doctor, the drug can be used by a person with a colo- or ileostomy. This is the surgical removal of a section of the small or large intestine through the anterior abdominal wall. Self-medication is unacceptable here.

Source: https://zaporamnet.ru/lechenie/lekarstva/dyufalak.html

How long can you take Duphalac?

Due to the slow action of the drug and the gradual colonization of the intestines by beneficial microorganisms, the course of treatment with Duphalac is on average 2-3 weeks . It is believed that during this time the intestines are populated with beneficial bacteria in sufficient quantities to ensure regular bowel movements. Sometimes one dose of the drug is enough to treat rare constipation. But to ensure a long-lasting and lasting effect, it is recommended to take Duphalac in courses.

Duphalac is a safe remedy, so sometimes its course of treatment can last more than six months. In this case, it is necessary to monitor blood counts for electrolyte levels. If symptoms return after stopping the drug, the doctor may recommend taking the drug further, but in a lower concentration. In this case, a specialist may recommend taking weekly breaks to prevent side effects.

The drug is not addictive, therefore it is safe for long-term and frequent use. Therefore, you can take Duphalac from several days to several months. But, despite its safety, Duphalac, like any other medicine, has contraindications and side effects, so before using it, consultation with a specialist is necessary. Only a doctor can prescribe the correct dosage and duration of treatment.

Recommendations for admission

In addition to the time of administration, to increase the effectiveness of the drug, other rules should be followed:

• Duphalac should be taken with plenty of liquid. After all, to achieve a laxative effect, liquid must be present in the intestines;
• Regardless of the frequency of administration, the laxative should be taken at the same time;
• It is forbidden to take the drug without consulting a doctor, or to exceed the prescribed dosage;
• The drug can be drunk unchanged or diluted;
• When taking other medications, a 2-hour interval should be observed;
• Therefore, if taking other medications is prescribed in the morning, then in this case it is better to drink Duphalac before bed.

From all of the above, we can conclude that at the initial stage of treatment, Duphalac is best taken in the morning. Further, depending on the individual reaction, you can take a laxative at night.