Trimedat and duspatalin can be taken simultaneously

Indications for use of Duspatalin

Duspatalin is used for the following diseases and conditions:

• irritable bowel syndrome, accompanied by pain, cramping and discomfort in the intestinal area;
• colic of intestinal or biliary origin;
• spasm of the digestive system caused by chronic gastrointestinal pathology;
• irritable bowel syndrome;
• pain caused by pancreatitis.

Treatment with Duspatalin for children with digestive system problems is possible only from 12 years of age.

Duspatalin - instructions for use

According to the instructions for use of Duspatalin, the drug is administered orally, 1 capsule 2 times a day, morning and evening. No dosage adjustment is required for older patients or patients with renal or hepatic insufficiency.

How to take Duspatalin before or after meals

It is necessary to drink Duspatalin 20 minutes before breakfast and dinner, washing down the capsules with a sufficient amount of water, which are swallowed whole and not chewed.

Duspatalin tablets or capsules – which is better, what’s the difference?

The drug is commercially produced in 2 dosage forms. The advantage of capsules is that they contain a larger volume of active substance compared to tablets. In addition, the capsules have a prolonged effect. For the treatment of gastrointestinal diseases accompanied by spasms, capsules are the best.

Antispasmodic agent JSC

Hi all!

Today we will talk about the most valuable thing, health!

After maternity leave, I got a job and then off we go: cakes, pies, sausage, coffee and all sorts of other junk food, all the time, sometimes it’s a holiday, sometimes there are sweet tooth lovers who constantly buy something and treat them, and when there’s... table, it is very difficult to refuse.

As a result, after a year of working in this mode, plus before, I loved to eat sweets, my pancreas gave in and wild pains and spasms began in my left side, my stomach swelled up like a ball, I didn’t understand what happened and first went for an ultrasound of the abdominal cavity, where I wrote a diagnosis - dilation of the loops of the large intestine in the splenic angle.

//www.youtube.com/watch?v=ylZyjXjAF-Y

I quickly went to the gastroenterologist with the same legs, because the pain was unbearable, it was even hard to work, it was even hard to lie at home.

He said that the expansion of the intestines is just gases (in fact, my stomach was so swollen that it didn’t even retract), and the reason for this was indigestion in the upper sections, in the stomach and pancreas, diagnosed gastroduodenitis and pancreatic dysfunction, until pancreatitis was diagnosed , told me to take additional tests.

Plus, before that, according to an ultrasound, I had a constant stagnation of bile due to a congenital bend of the gallbladder, which I treated only that year with Livodex; the doctor said that this long-term stagnation also greatly affected the pancreas.

The gastroenterologist first prescribed me a strict diet - table No. 5, so goodbye to everything fatty, all cakes and pastries)) Only non-fried and non-fatty foods are allowed. You can read more about this diet on the Internet. I knew about this diet, but recently I’ve relaxed a lot in my diet, which is why I ruined my health and gained several kg.

Now I intend to completely reconsider my diet on an ongoing basis, and not as a temporary restriction, since the pancreas is a bad joke, and diabetes is not far away, and I don’t want that.

As for medications, the doctor prescribed me a drug against spasms and pain - this is either Duspatalin or Sparex.

Having looked at the prices of the drugs, as you already understood, I chose the less expensive Sparex.

I don't understand why there are so few reviews about him here.

Compound:

• Active substance: mebeverine hydrochloride 200 mg;

• Excipients: colloidal silicon dioxide (Aerosil), hypromellose (hydroxypropyl methylcellulose brand Benecel MP 874), povidone (Plasdon K 90, Kollidon 90 F), magnesium stearate;

The price of 1 package of Sparex is 314 rubles.

There are 30 capsules in a pack.

Manufacturer – Russia, Moscow region.

For comparison, Duspatalin 30 capsules costs 482 rubles (Manufacturer: Germany).

Pharmacological action - antispasmodic.

Antispasmodic myotropic action, has a direct effect on the smooth muscles of the gastrointestinal tract (mainly the large intestine). Eliminates spasm without affecting normal intestinal motility. Does not have anticholinergic effects.

Yellow capsules, 2 blisters of 15 capsules.

Dispensed by prescription. Nobody asked me about it.

The drug helped me a lot, but the result did not appear immediately, the doctor prescribed me a course of 3-4 weeks, I noticed an improvement after about a week, I bought 2 packs for a month’s course.

You need to drink 2 capsules a day, one in the morning, the other in the evening 20 minutes before meals, that is, one package is enough for 15 days.

Now I’ve been taking the drug for about 3 weeks, the bloating has gone away, but I’ll say there are still a few cramps sometimes, I think the pancreas will take a long time to restore its activity and the main thing is now to also stick to the diet.

Together with Sparex, the doctor also prescribed Nolpaza, since high acidity and enzyme preparations are often a concern, which also affected the result of treatment, I will talk about them in the following reviews.

Based on the results of treatment with Sparex, I am very pleased, so I confidently recommend it to everyone, its composition is the same as Duspatalin, the only difference is that Duspatalin is an imported drug, and Sparex is domestic.

I agree that it happens that an imported drug is better than ours (I had experience with Phlebodia and Venarus, for example), but sometimes there is no difference, and our manufacturers, on the contrary, want to make the drugs more accessible to Russians.

Reviews of other drugs:

Hepatoprotector Legalon - an assistant for your liver

Itomed – for gastritis and reflux esophagitis

Source: //irecommend.ru/content/analog-dyuspatalina-po-priemlemoi-tsene-sovetuyu-pri-bolyakh-i-spazmakh-v-kishechnike-i-drug

Analogues of Duspatalin

The pharmacological industry produces a wide range of analogues and substitutes for Duspatalin. These drugs are sold in pharmacies under the guise of:

• generics;
• synonyms;
• mono- and combined drugs.

A large selection of Duspatalin substitutes from Russian and foreign manufacturers significantly expands the therapeutic capabilities of the doctor. This allows him to take into account all the nuances of gastrointestinal diseases in both adults and children when prescribing medication.

Table of Duspatalin analogues with price and country of origin.

Prices for Duspatalin analogues vary widely and depend on the manufacturer and the ingredients that make up the medicine. A large selection of drugs with similar indications allows you to purchase Duspatalin substitutes at a budget cost, but with a high therapeutic effect.

What else can replace Duspatalin, what analogues? The list of medications used to relieve spasms in various gastrointestinal diseases can be supplemented with the following drugs:

• Duphalac;
• Creon;
• Hilak forte;
• Dutan;
• Acipol.

From this list of Duspatalin analogues, some drugs can only be purchased with a prescription, and some drugs can be purchased without it. In pharmacies you can find Duspatalin analogues cheaper than their base drug.

Kolofort

Manufacturer: NPF MATERIA MEDICA HOLDING (Russia)
Release form: lozenges

Active ingredient: antibodies to human TNF, to brain-specific protein S-100, to histamine

The combination of active substances in the combined preparation helps to normalize the nervous and humoral regulation of intestinal function. As a result of the action of Kolofort, the negative manifestations of the disease are stopped. This occurs due to the relaxation of smooth muscles and a decrease in the tone of the wall of the digestive organ.

An analogue of Duspatalin is prescribed, 1-2 tablets 2 times a day by completely resolving them. The duration of treatment is 1–3 months, which can be extended according to indications.

Drotaverine

Manufacturer: UPDATE (Russia)
Release form: tablets

Active ingredient: drotaverine hydrochloride

Drotaverine is a Russian analogue of Duspatalin and is classified as a myotropic antispasmodic. It is similar to Papaverine in its chemical structure and pharmacological action. But it differs from it in a stronger and longer-lasting effect.

The analog relieves spasm of the smooth muscles of internal organs, reduces intestinal motility, dilates blood vessels and reduces blood pressure. The drug is prescribed 1-2 tablets 2-3 times a day.

Espumisan

Manufacturer: BERLIN-CHEMIE, AG (Germany)
Release form: capsules

Active ingredient: simethicone

Espumisan belongs to the group of carminatives, which helps reduce gas formation in the intestines, preventing bloating and the occurrence of intestinal colic. This analogue of Duspatalin is included in the preparation of the patient before instrumental methods of examining the gastrointestinal tract and pelvic organs (ultrasound, MRI, radiography).

The medication is prescribed 2 capsules 3-5 times a day, depending on the indications. It is possible to adjust the dosage of the drug. The duration of its use is determined by the doctor.

Ganaton

Manufacturer: ABBOTT LABORATORIES (Germany)
Release form: tablets

Active ingredient: itopride

Ganaton, an analogue of Duspatalin in tablets, is a stimulator of gastrointestinal tone and motility. As a result of the action of the medication, accelerated evacuation of food contents from the stomach occurs, suppression of the gag reflex, and elimination of heaviness and discomfort in the abdomen.

The analogue is prescribed 1 tablet 3 times a day. According to indications, it is possible to adjust the dosage towards its reduction. The course of treatment with the drug can be up to 2 months.

Odeston

Manufacturer: ADAMED PHARMA (Poland)
Release form: tablets

Active ingredient: hymecromone

Odeston belongs to the group of medications that have a choleretic effect. Duspatalin analogue stimulates the formation and secretion of bile. Acting as an antispasmodic on the bile ducts and sphincter of Oddi, the drug does not reduce gastrointestinal motility and blood pressure.

The analog prevents the stagnation of bile and the formation of cholesterol crystals, that is, the formation of stones in the gallbladder. The drug is prescribed 1-2 tablets 3 times a day, lasting 15-20 days.

De Nol

Manufacturer: ASTELLAS PHARMA EUROPE (Netherlands)
Release form: tablets

Active ingredient: bismuth tripotassium dicitrate

Duspatalin analog De-Nol has an antibacterial effect against a number of pathogens, including Helicobacter pylori. Due to the active ingredient included in the medication, the resistance of the gastric mucosa to the aggressive action of pepsin increases. The drug relieves negative symptoms in the following conditions:

• with exacerbation of stomach and duodenal ulcers;
• chronic gastritis;
• with irritable bowel syndrome accompanied by diarrhea.

The analogue is prescribed 1 tablet 4 times a day or 2 tablets 2 times a day. The duration of treatment is determined by the doctor.

Antispasmodic for the intestines

Our readers successfully use Monastic Tea to treat gastritis and ulcers. Seeing how popular this product is, we decided to bring it to your attention. Read more here...

Diseases of the gastrointestinal tract are often accompanied by pain. It is caused by a spasm of smooth muscles and can be unbearable. Drugs that can relieve muscle spasms are antispasmodics. There is an extensive list of medications that relieve intestinal discomfort. It is useful for every person to learn to understand them.

If you have pain in the intestines due to illness, it is permissible to take antispasmodics to eliminate the discomfort.

• 1 What types of antispasmodics are there?

• 1.1 Neurotropic antispasmodics
• 1.2 Myotropic drugs
• 1.3 Neuromyotropic drugs
• 1.4 Complex antispasmodic drugs
• 1.5 Antispasmodic herbs for the intestines

• 2 When to use and how to treat?
• 3 Contraindications
• 4 What else is important?

What types of antispasmodics are there?

The antispasmodic acts either directly on the muscles or on the process of transmitting impulses along nerve endings. There are also medications that combine both functions. The main goal is to relieve smooth muscle spasms. Smooth muscle is found in the skin, sensory organs, and forms internal organs and the walls of blood vessels. It obeys the autonomic nervous system.

Drugs that help with cramps are available in the form of:

• tablets;
• tinctures;
• capsules;
• candles;
• drops;
• ampoules;
• herbal preparations.

Depending on the mechanism of action, certain groups of medications are distinguished.

Return to contents

Neurotropic antispasmodics

Neurotropic antispasmodics act directly on the central nervous system, blocking pain in the intestines.

Such pharmaceuticals prevent nerve impulses from traveling directly from the brain to the muscles. Some of them affect the brain itself. There are also more selective ones, they work locally with nerve endings in the muscles of the gastrointestinal tract. The action of these drugs is based on M-anticholinergics.

It should be remembered that neurotropic substances that affect the brain have side effects. Heartbeats may become more frequent, blood pressure may increase, and neurohumoral function (one of the forms of body regulation) decreases.

A product that works directly with receptors is more gentle. It only affects pain in the intestines and does not affect other human organs.

Return to contents

Myotropic drugs

Such antispasmodics do not affect the nervous system at all. These are substances that work in muscles. They do not allow potassium ions and some enzymes to enter the cells, which reduces pain. Such medications are often prescribed for intestinal disorders. They may be based on:

• drotaverine (the most famous is “No-Shpa”);
• papaverine (the most famous is “Papaverine”);
• mebeverine (“Niaspam”, “Sparex”);
• trimebutin (“Trimedat” and “Neobutin”).

Return to contents

Neuromyotropic drugs

This group combines both activities. This effect is achieved through a combination of two or more active ingredients.

Herbal antispasmodic medications that block spasms. Some herbs have an effect on the intestinal muscles. Fennel, mint, belladonna, tansy, chamomile - these plants can remove spasms without side effects. Tablets, syrups and other preparations are made from them.

Neuromyotropic antispasmodics are also prescribed for children to eliminate intestinal pain.

Antispasmodics based on herbal components are often prescribed to children. Pain in the intestines can manifest itself literally from infancy in the form of colic. They cause great discomfort to the baby. Colic is not generally considered a disease, but despite this, it causes anxiety, disrupts the child’s sleep and routine, directly affects the general condition, and, moreover, causes a lot of trouble for parents.

Suffering can often be reduced with the help of special syrups and suspensions. Syrups based on herbal ingredients are often prescribed. For example, Plantex blocks spasms in the intestines and is safe for children. The drug “Azulan” is made based on chamomile, “Tanacehol” is based on tansy. There are other similar drugs.

Return to contents

Complex antispasmodic drugs

This is a complex of substances that relieves spasms and other symptoms. For example, these medications can reduce fever and relieve inflammation. They will not only eliminate the pain, but also remove the cause of the disease. Thus, “Pentalgin” is prescribed not only in case of spasm, but also in case of fever. "Spazmolgon" effectively helps with pain and is prescribed for high blood pressure. Novigan is prescribed for intestinal colic; it also helps with migraines and joint pain. The versatility of such drugs makes them very popular.

Many plants have the ability to relieve pain, which can be used as an alternative solution to pills. Return to contents

Antispasmodic herbs for the intestines

The safest assistants with no contraindications. Herbs have long been used in the treatment of pain. Before buying tablets or syrups, you can take herbal decoctions: chamomile, oregano, tansy, calamus, immortelle, oregano. They are sold at the pharmacy in the form of ready-made preparations. There are special medicinal teas for children that help with colic.

Return to contents

When to use and how to treat?

Antispasmodic medications - tablets, syrups or suppositories for the intestines, are prescribed when a person is diagnosed with a disorder in the functioning of the gastrointestinal tract. Ailments such as gastritis, pancreatitis, and peptic ulcers are always accompanied by excruciating pain for a person. In this case, medications of this group reduce the manifestations of the disease, and in some cases also affect its cause: they reduce inflammation, tone, and fever. It should be remembered that only a doctor can choose the right drug.

The choice of pharmacological names is very extensive, and a specific one can be prescribed only by knowing the picture of the disease. For example, medications based on anticholinergics are prescribed, in addition to pain, for excessive secretion in the intestines. Similarly, a number of complex drugs are prescribed not only for pain, but also for other symptoms: fever, high blood pressure.

Duspatalin or Trimedat - which is better and more effective for pancreatitis and constipation

Manufacturer: VALENTA PHARM (Russia)
Release form: tablets

Active ingredient: trimebutine

Both drugs are antispasmodics, the action of which is aimed at reducing smooth muscle tone, normalizing digestion and intestinal motility. Medicines contain different active substances, which determine their different mechanisms of action.

At the initial manifestations of the disease or to prevent relapse, Duspatalin will be the best, since its effect is milder and weaker. It will be more effective for pain in the intestines, reducing spasms, but without affecting peristalsis. For bloating and constipation, the effect of Trimedat will be more effective, since after taking it, stool normalization occurs.

According to doctors and patients, both drugs are well tolerated and give the expected effect. In some cases, preference is given to Duspatalin (colic with pancreatitis, cholecystitis), and sometimes to its analogue Trimedat (for children after 3 years).

Platyfillin

Platyphylline for pancreatitis is a potent medicine that can be used as a substance for emergency care or in a hospital setting under the supervision of specialists. This means that this medication should never be taken on its own, because its effect on the body is not limited to its antispasmodic effect.

Like other drugs of a similar group, this medicine is aimed at relieving spasms from the smooth muscles of the gastrointestinal tract. To do this, patients are injected with no more than two milliliters of a 0.2% solution subcutaneously. The injection interval is twelve hours.

In cases of exceeding the dosage of Platiphylline for pancreatitis causes the following consequences:

• rapid heartbeat against the background of low blood pressure;
• dry mouth;
• hoarseness of voice;
• intestinal atony;
• disruption of the process of urine emission;
• attacks of severe headache and dizziness;
• seizures;
• photophobia.

Duspatalin or Sparex - which is better, what is the difference

Manufacturer: KANOPHARMA PRODUCTION (Russia)
Release form: capsules

Active ingredient: mebeverine

Both drugs have the same active substance and mechanism of action. The difference between the medications is noted:

• in the country of origin;
• in additional ingredients in medications;
• in dosage forms;
• in the cost of funds.

Sparex is an analogue of Duspatalin in capsules, like the base drug, it relieves spasm of the smooth muscles of the gastrointestinal tract. But the effect of its action is more pronounced in the area of ​​the large intestine, so it will be best for diseases of this area of ​​​​the digestive organ. This is confirmed by reviews of patients who took this Russian analogue.

Reasons for special demand

The popularity of the drug is due to several factors:

• Efficiency. Unlike analogues, Duspatalin capsules and tablets act much faster and last longer. Relief occurs within 15 minutes, whereas with other antispasmodics you need to wait 20-40. The effect lasts for about 8 hours, which allows you to use only 2 capsules per day. The drug, thanks to its special coating, safely penetrates the acidic environment of the stomach and penetrates the intestinal tissue, producing a therapeutic effect.
• Quality. The drug is produced in developed countries, where quality, safety, and effectiveness are strictly controlled. Production facilities are located in the Netherlands, USA, France, Germany. It has been repeatedly noticed by users that analogues with an equal amount of the active component are weaker.
• Safety. Duspatalin does not cause side effects when used correctly; cases of overdose are excluded. The active substances act directly on the muscles of the gastrointestinal tract without disturbing other functions of the system or internal organs. Decomposition products do not cause intoxication and leave the body in urine and partly in feces.
• Can be taken during pregnancy and breastfeeding. The studies were carried out in laboratory conditions on animals. As a result, no pathological effects on the development of the fetus or the condition of the female were revealed. Such experiments have not been carried out on women, so theoretically there are concerns. Prescribed under the supervision of a specialist in urgent need. The situation is similar with breastfeeding women. According to the manufacturers, the active substances do not pass into breast milk.
• Minimum list of contraindications. The main prohibition is the presence of individual intolerance to the components. This happens rarely, the drug is well tolerated and does not cause side effects. In case of an overdose, accidental or intentional, an allergic reaction to the skin, dizziness, headache, weakness, diarrhea, nausea, palpitations, and nervous agitation occurs. There is no special therapy, treatment is symptomatic. Reduce the dosage or abandon the drug. In severe cases, the stomach is washed.
• Possibility to combine with other medications. Treatment of pancreatitis involves the simultaneous use of several drugs with different mechanisms of action. Duspatalin goes well with antacids, prokinetics, proton pump inhibitors, sorbents, antibiotics, and anti-inflammatory drugs. The break between taking medications should be at least 20 minutes.

The opportunity to leave reviews on the Internet contributed to the emergence of special demand. Users evaluate the quality of the drug, its effectiveness, and share their personal experiences. Most reviews are positive, confirming the high effectiveness and safety of the medication.

You can buy Duspatalin at a pharmacy; if you wish, you can order it online. It is available without a prescription, but you must first consult a specialist to know what to treat and how to do it correctly. The shelf life of capsules and tablets is 3 years from the date of manufacture. Store away from direct sunlight. The price of a package with 10, 15 tablets is on average 500 rubles.

Duspatalin or Buscopan - which is better for pancreatitis

Manufacturer: SANOFI RUSSIA (Russia)
Release form: tablets

Active ingredient: hyoscine

Buscopan and Duspatalin are myotropic antispasmodics that relieve spasms in the gastrointestinal tract. When relieving pain due to the development of colic, the best drug is Buscopan. Its advantage is manifested in the speed of relief of the attack.

A decrease in pain intensity occurs within a quarter of an hour from the moment the medication enters the intestines. The analogue is used in a short course of 1–2 days in acute conditions. Duspatalin will be the best for long-term treatment of chronic bowel dysfunction.

Atropine

During therapy, Atropine is often administered in combination with an anesthetic substance. This drug is used only according to strict indications and mandatory supervision by specialists. This is due to the fact that it can cause a number of side effects, including:

• increased heart rate;
• severe dizziness and headache;
• bowel dysfunction in the form of constipation;
• reducing the number of urges to urinate;
• increasing indicators of intraocular tone.

Due to the fact that almost all antispasmodics have serious side effects, the attending physician decides how to take such medications individually for each patient.

Duspatalin is a popular drug that is a myotropic antispasmodic. In other words, the medicine can have an analgesic effect by suppressing spasms, relaxing the intestinal muscles. An important advantage is that while relieving attacks, the drug does not provoke peristaltic contractions. Thus, there is no need to worry about delays in food progress. The desired result is achieved 15 minutes after administration and lasts for a long time, up to several hours.

Duspatalin or No-shpa - which is better

Manufacturer: Chinoin Pharmaceutical and Chemical Works Co.
(Hungary) Release form: tablets, solution for parenteral administration

Active ingredient: drotaverine

Both drugs have the same effect from use, but different active substances and mechanism of action. No-spa has broader indications, relieves pain faster and is the best drug for pancreatitis, spasms, and pain of various origins. The use of Duspatalin is preferable for diseases of the stomach and intestines.

Duspatalin or Neobutin

Manufacturer: FP OBOLENSKOE (Russia)
Release form: tablets

Active ingredient: trimebutine

Medicines contain various active substances that act on the gastrointestinal tract in different ways. Duspatalin relieves spasm accompanied by pain, affecting its cause.

Neobutin eliminates pain by normalizing the sensitivity of visceral receptors in case of digestive and peristalsis disorders, accompanied by changes in constipation and diarrhea.

Duspatalin or Niaspam - which is better?

Manufacturer: Sun Pharmaceutical Industries (India)
Release form: capsules

Active ingredient: mebeverine

Both drugs have the same active substance, mechanism of action, and release form (capsules). The difference between the basic medicine and its analogue is only in the auxiliary ingredients in the medicine.

The results obtained from treatment with Duspatalin or Niaspam will be equivalent. The choice of the best drug belongs to the doctor, taking into account concomitant diseases and the degree of their activity.

Duspatalin or Meteospasmil - which is better?

Manufacturer: Laboratories MAYOLY-SPINDLER (France)
Release form: capsules

Active ingredients: alverine, simethicone

Duspatalin and its analogue Meteospasmil have different active substances and mechanisms of action, but the same treatment result. The choice of medication depends on the functional state of the digestive system.

Duspatalin will be best if the pain comes from the liver, pancreas, or gall bladder. That is, the basic drug has broader indications compared to its analogue.

Duspatalin or Dicetel - which is better?

Manufacturer: ABBOTT LABORATORIES (Germany)
Release form: tablets

Active ingredient: pinaveria bromide

Both medications have an antispasmodic effect. Dicetel is able to reduce the concentration of hydrochloric acid in the stomach and stimulate the evacuation of its contents. Its use is effective for mild gastrointestinal disorders accompanied by eating errors and pain.

The effectiveness of Duspatalin will be higher in the treatment of diseases of the pancreas, gall bladder, and irritable bowel syndrome.

Properly selected analogues of Duspatalin for children and adults with organic and functional pathologies of the gastrointestinal tract will allow the doctor to effectively carry out treatment and relieve negative symptoms.

Characteristics of Trimedat

Trimedat interacts with the motility of the gastrointestinal tract, relieving the symptoms accompanying its disturbance and regulating the intensity of food movement between the esophagus and the colon. Eliminates diarrhea, dyspepsia, constipation, nausea and vomiting, intestinal spasms and colic, increased gas formation.

Trimedat eliminates intestinal spasms and colic.

The drug works throughout the entire digestive tract, affecting the rate of bowel movement, reduces the pressure exerted by the sphincter, helps increase the sensitivity of smooth muscles to food irritants, and normalizes the natural activity of the muscles of the small and large intestines in diseases of the digestive system.